Faculty of Chemistry & Biochemistry
Macromolecular, cryo-electron microscopy and three-dimensional (3D), image-reconstruction techniques are used in our research to visualize viruses and to determine how they interact with their hosts, replicate and... more
We develop chemical and spectroscopic tools for structural biology of complex biological systems.... more
Our interdisciplinary research group focuses on chemical biology with an emphasis on developing novel reactions for addressing questions in bottom-up synthetic biology and molecular imaging.
Our lab studies how the glycocalyx of living cells – a complex ensemble of glycoproteins and glycolipids on the cell surface – mediates their interactions with the outside world.
Work in the Komives Lab is focused on understanding the parameters that govern protein-protein interactions mediated by non-globular proteins. Three main systems are currently under study.
|J. Andrew McCammon||
Most chemical reactions are carried out in solution. The solvent surroundings affect such reactions in a variety of important... more
The overall goal of the research program is to develop protein expression systems, instrumentation, and experimental methods so that NMR spectroscopy can be used to study all of the proteins encoded in a genome.
We synthesize nanomaterials and study their chemistry, electrochemistry, and optical properties. Our emphasis is on nanophase silicon and iron oxide-based materials.
We study how cells make proteins, which is a fundamental process for life. Ribosomes are the machines responsible for protein synthesis in all cells. Ribosomes accurately "read" the... more
We are studying the structure, dynamics, and localization of cAMP-dependent protein kinase. PKA is a prototype for the protein kinase superfamily involved in signal transduction.
The Villa Lab develops tools to observe macromolecular complexes in their natural environment, the cell. Our ultimate goal is to unveil the structural dynamics of these complexes while... more
Our lab takes an interdisciplinary approach to try and understand the specificity of mRNA localization to membrane-less compartments during stressful environmental conditions. In the long term we are interested in... more