rallipalli

Kartik Lakshmi
Rallapalli
Research Description: 

Many-Body representation of base-editing CRISPR-Cas9

The goal of my research is to use multi-scale computational simulation models to study the structural and energetic changes induced due to specific mutations in the base-editing domain of ABE(Adenine Base Editors).  The results will allow us to understand directed evolution of proteins and to predict mutations so as to evolve more DNA editing porteins.

http://paesanigroup.ucsd.edu/

Graduate Program: 
Chemistry and Biochemistry
Department(s): 
Chemistry and Biochemistry