Domain Science
Dr. Villa's research spans multiple areas of biomedical science, including the role of the protein LRRK2 in Parkinson's Disease, the replication cycle of jumbo phage that create a compartment in bacteria resembling the eukaryotic nucleus, as well as several aspects of the eukaryotic nuclear periphery, including the structural dynamics of the nuclear pore complex, chromatin, and mechanotransduction between the nucleus and the cytoplasm.
Technology
Dr. Villa offers research training in cryo-electron tomography, ideally suited for bridging scales between structural and cellular biology. Her lab also works on biophysical methods for structure determination including multi scale integrative modeling of macromolecular complexes.