In this talk, we will discuss a novel approach to biomolecule quantification and detection using graphene field-effect transistor technology. We will illustrate the role of graphene in the field of biosensors as well as the fundamental physics that enable the material to act as a highly sensitive and valuable signal transducer. A discussion of ssDNA aptamers and their capabilities for biosensing will be discussed. In particular, we will present a design of a platform biosensing technology utilizing the combined selectivity and specificity of ssDNA aptamers and the graphene electrochemical properties for signal transduction. We will explain current and past work using this technology to detect SARS-CoV2 and neurodegenerative proteins in simple and complex biological fluids. This will lead the discussion to our current efforts to develop a high-throughput mulitplexed GFET array interfaced with a custom low-energy CMOS-IC for rapid proteomic quantification.

The video of this presentation is available here.