Domain Science
The Obara Lab is interested in how complex, self-maintaining cellular systems are assembled from individual molecular components. We work in numerous biological systems, including the basis of human aging, models of neurodegenerative or neuromuscular disease, the underlying physics of metabolism, and others. The common thread in our work is the combination of new tools and fundamental biological processes examined at multiple scales.
Technology
Our lab specializes in the development and application of advanced imaging technologies to solve fundamental questions in cell biology, immunology, and neuroscience. We integrate classical biophysics and biochemistry approaches with next-generation optical and electron microscopy to observe the behavior of single biomolecules in the context where they exist in living cells.